KOLLAGENNING INSON ORGANIZMIDAGI BIOLOGIK O‘RNI VA AYOLLAR SALOMATLIGIDAGI AHAMIYATI
Keywords:
kollagen, kollagen peptidlari, biriktiruvchi to‘qima, teri, suyak, tog‘ay, osteoporoz, estrogen, menopauza, teri elastikligi.Abstract
Kollagen inson organizmidagi eng ko‘p uchraydigan strukturaviy oqsillardan biri bo‘lib, biriktiruvchi to‘qimalarning asosiy komponentini tashkil etadi. U teri, suyak, tog‘ay, pay, boylam, qon tomirlari va boshqa ko‘plab to‘qimalarning mexanik mustahkamligi, elastikligi va yaxlitligini ta’minlashda muhim rol o‘ynaydi. Kollagenning biologik ahamiyati faqat strukturaviy vazifa bilan cheklanmay, hujayralararo signalizatsiya, yara bitishi, to‘qimalarning qayta tiklanishi va hujayralarning faoliyatini boshqarishda ham namoyon bo‘ladi.
Ayollar organizmida kollagen almashinuvi yosh, gormonal holat, ovqatlanish, quyosh nurlanishi, oksidlovchi stress va boshqa omillarga bog‘liq. Ayniqsa menopauza davrida estrogen darajasining pasayishi kollagen sintezining kamayishi bilan bog‘liq bo‘lib, terining elastikligi pasayishi, ajinlar paydo bo‘lishi va suyak massasining kamayishiga hissa qo‘shishi mumkin. Og‘iz orqali qabul qilinadigan gidrolizlangan kollagen peptidlarining teri namligi va elastikligiga ta’siri bo‘yicha klinik tadqiqotlar mavjud bo‘lsa-da, ularning barcha kosmetik va sog‘liq uchun da’vo qilinadigan ta’sirlari bir xil darajada isbotlangan emas.
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