DVS-SINDROM: PATOGENEZ, KLINIK KECHISH VA TASHXIS ASOSLARI
Keywords:
DVS-sindrom, gemostaz, mikrotromboz, koagulyatsiya, patogenez, klinik belgilari, tashxis.Abstract
DVS-sindrom (disseminatsiyalangan tomir ichi ivish sindromi) — bu gemostaz tizimining og‘ir buzilishi bo‘lib, unda qon ivish jarayoni nazoratdan chiqadi va tomir ichida keng ko‘lamda mikrotromblar hosil bo‘ladi. Ushbu maqolada DVS-sindromning patogenezi, asosiy bosqichlari, klinik kechish shakllari va tashxis mezonlari yoritilgan. Shuningdek, laborator ko‘rsatkichlar orqali sindromni erta aniqlashning ahamiyati va differensial tashxisning roli tahlil qilingan. Maqola shifokorlar, laborator mutaxassislar hamda klinik diagnostika bilan shug‘ullanuvchi tibbiy xodimlar uchun mo‘ljallangan.
References
Levi, M., & Toh, C. H. (2025). Disseminated Intravascular Coagulation: Pathophysiology and Clinical Management. Frontiers in Medicine, 12(1502628).
Iba, T., & Levy, J. H. (2024). Sepsis-Induced Coagulopathy and DIC: New Diagnostic Perspectives. Journal of Intensive Care, 13(7), 45–57.
Wada, H., Thachil, J., & Levi, M. (2023). Diagnosis and Treatment of Disseminated Intravascular Coagulation According to Current Guidelines. Thrombosis Research, 228, 15–27.
Okamoto, K., et al. (2025). Recent Trends in Disseminated Intravascular Coagulation Mortality in Japan. JMA Journal, 8(2), 134–140.
Taylor, F. B., et al. (2022). Towards a Scientific Definition of DIC and Sepsis-Associated Coagulopathy. Critical Care Medicine, 50(4), 600–610.
Gando, S., et al. (2023). Disseminated Intravascular Coagulation in Critically Ill Patients: A Multicenter Observational Study. PLOS ONE, 18(9): e0330842.
Levi, M., & Scully, M. (2021). How I Treat Disseminated Intravascular Coagulation. Blood, 137(17), 2101–2112.
Ghosh, K., & Mukherjee, S. (2025). Emerging Biomarkers in DIC Diagnosis and Management. International Journal of Hematology, 122(3), 411–420.
Toh, C. H., & Hoots, W. K. (2022). The Scoring System for Disseminated Intravascular Coagulation: ISTH and JAAM Criteria Compared. Seminars in Thrombosis and Hemostasis, 48(6), 585–593.
Koyama, K., et al. (2024). Artificial Intelligence-Assisted Early Detection of DIC in ICU Patients. Nature Digital Medicine, 7(1), 89–96.
