OG‘IZ BO‘SHLIG‘I KASALLIKLARIDA FERMENTATIV VA METABOLIK O‘ZGARISHLAR
Keywords:
kariyes, pulpit, gingivit, periodontit, dental blyashka, demineralizatsiya, remineralizatsiya, og‘iz suyuqligi, oksidlovchi stress, sitokinlar, kollagen metabolizmi, bioximik jarayonlar.Abstract
Ushbu maqolada tishlarda uchraydigan asosiy kasalliklarda kechadigan biokimyoviy jarayonlar tizimli ravishda tahlil qilinadi. Tish emali va dentin demineralizatsiyasi, og‘iz suyuqligining himoya xususiyatlari, dental blyashka metabolizmi, yallig‘lanish mediatorlari, oksidlovchi stress, kollagen parchalanishi hamda pulpa va periodontal to‘qimalardagi almashinuv o‘zgarishlari ilmiy jihatdan yoritilgan. Kariyes, pulpit, gingivit va periodontit misolida uglevodlar fermentatsiyasi, kislota-ishqor muvozanati buzilishi, fermentlar faolligining o‘zgarishi va sitokinlar kaskadi klinik belgilar bilan bog‘lab tushuntirilgan. Shuningdek, remineralizatsiya, antioksidant himoya, so‘lakning bufer tizimi va profilaktik choralarning patogenetik asoslari ham ko‘rsatib berilgan. Maqola stomatologik kasalliklarning molekulyar asoslarini chuqurroq anglashga, erta profilaktika va individual davolash strategiyalarini ishlab chiqishga xizmat qiladi.
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