FETOPLATSENTAR KOMPLEKSDA QON AYLANISHINING REGULYATSIYASI VA PLATSENTAR YETISHMOVCHILIKNING PATOGENETIK ASOSLARI.
Ключевые слова:
fetoplatsentar kompleks, uteroplatsentar qon aylanishi, platsentar yetishmovchilik, gemodinamika, endotelial disfunksiya, oksidlovchi stress, angiogenez, homila gipoksiyasi, intrauterin o‘sishning cheklanishi.Аннотация
Ushbu maqolada fetoplatsentar kompleksda qon aylanishining fiziologik regulyatsiyasi, uteroplatsentar gemodinamikaning shakllanish mexanizmlari hamda platsentar yetishmovchilikning patogenetik asoslari tahlil qilinadi. Platsentar qon oqimining buzilishida tomirlar qarshiligi, endotelial disfunksiya, oksidlovchi stress, angiogen omillar muvozanati va ona organizmidagi tizimli o‘zgarishlarning ahamiyati yoritiladi. Shuningdek, platsentar perfuziyaning pasayishi homilada surunkali gipoksiya, o‘sishning cheklanishi va perinatal asoratlar rivojlanishiga olib keluvchi mexanizmlar nuqtayi nazaridan ko‘rib chiqiladi. Mavzu zamonaviy patofiziologik qarashlar asosida tahlil qilinib, platsentar yetishmovchilikni erta aniqlash va uning oqibatlarini kamaytirishning klinik ahamiyati asoslanadi.
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